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Physical Biology of the Cell

Rob Phillips, Jane Kondev, Julie Theriot

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  • Movies (14)

    Viewing 1 - 10 of 14 results
    • Movie 3.1 Neutrophil Chase (Referenced in Figure 3.3)

      [video/quicktime, 5.28 MB]

      Chapter Name:
      Chapter 3: When: Stopwatches at Many Scales
      Description:
      This classic movie was made by David Rogers at Vanderbilt University in the 1950s. It shows a neutrophil (a type of white blood cell) chasing a bacterium through a field of red blood cells in a blood smear. After pursuing the ...
    • Movie 3.2 Early Embryonic Cell Division (Referenced in Figure 3.10)

      [video/quicktime, 1.72 MB]

      Chapter Name:
      Chapter 3: When: Stopwatches at Many Scales
      Description:
      This video shows the remarkable synchrony of the early embryonic cell divisions for the clawed frog Xenopus laevis. About 25 frog eggs were fertilized simultaneously in this petri dish, and then filmed over the first dozen ...
    • Movie 3.3 Eukaryotic Cell Division (Referenced in Figure 3.15)

      [video/quicktime, 3.23 MB]

      Chapter Name:
      Chapter 3: When: Stopwatches at Many Scales
      Description:
      This video sequence shows some of the events of the eukaryotic cell cycle, for an individual mammalian cell growing in tissue culture. This living cell is observed using differential interference contrast microscopy. At the start ...
    • Movie 3.4 Myosin Steps (Referenced in Figure 3.26)

      [video/quicktime, 1.12 MB]

      Chapter Name:
      Chapter 3: When: Stopwatches at Many Scales
      Description:
      In this experiment, a single fluorescent molecule was attached to one of the two actin-binding motor heads on a molecule of myosin V. As the motor protein steps along the actin filament, the fluorescent spot changes its location ...
    • Movie 10.1 DNA Packaging (Referenced in Figure 10.18)

      [video/quicktime, 3.91 MB]

      Chapter Name:
      Chapter 10: Beam Theory: Architecture for Cells and Skeletons
      Description:
      This animation illustrates the packaging of DNA into the capsid head of bacteriophage phi-29. From cryo-electron microscopy, it appears that the DNA is packaged as a series of near-concentric hoops inside the rigid phage capsid. ...
    • Movie 10.2 DNA Twist Elasticity Experiment (Referenced in Figure 10.39)

      [video/quicktime, 3.47 MB]

      Chapter Name:
      Chapter 10: Beam Theory: Architecture for Cells and Skeletons
      Description:
      This experiment was designed to measure the twist modulus of DNA. A double-stranded DNA molecule (which is not visible here) has been stretched between two large beads, shown at the top and bottom of the video frame. The upper ...
    • Movie 11.1 Force-Induced Tether Formtion (Referenced in Figure 11.25)

      [video/quicktime, 2.61 MB]

      Chapter Name:
      Chapter 11: Biological Membranes: Life in Two Dimensions
      Description:
      This experiment was designed to measure the amount of force required to pull a membrane tether from a spherical vesicle. This large phospholipid vesicle was made by including a small fraction of biotinylated lipid molecules, so ...
    • Movie 11.2 Cell Compartments Tomography (Referenced in Figure 11.34)

      [video/quicktime, 13.94 MB]

      Chapter Name:
      Chapter 11: Biological Membranes: Life in Two Dimensions
      Description:
      The precise three-dimensional shapes of all the membrane-enclosed organelles within a cultured cell can be painstakingly reconstructed using electron tomography. Here, we see the region surrounding the Golgi apparatus in an ...
    • Movie 13.1 Transport Within a Nerve Cell (Referenced in Figure 13.05)

      [video/quicktime, 4.07 MB]

      Chapter Name:
      Chapter 13: A Statistical View of Biological Dynamics
      Description:
      In nerve cells, passive diffusion is insufficient to transport large membrane-enclosed organelles down the length of the axon, which can range in length from under one millimeter to over a meter. Rapid directed transport in these ...
    • Movie 15.1 Keratocyte (Referenced in Figure 15.02)

      [video/quicktime, 3.94 MB]

      Chapter Name:
      Chapter 15: Rate Equations and Dynamics in the Cell
      Description:
      This video sequence shows a single fish skin cell moving across the field of view. The cell body, containing the nucleus and all the membraneous organelles, is at the left side. The large, broad, flat lamellipodium that pulls the ...
    Viewing 1 - 10 of 14 results
  • Other Resources (1)

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    • Hints for the Problems in Physical Biology of the Cell

      [application/pdf, 874.08 kB]

      Chapter Name:
      Multiple Chapters
      Description:
      This PDF provides both hints and strategies for attacking some of the more difficult end-of-chapter problems. In some cases, the hints provide intuition about how to set up the problem; in other cases, the hints provide explicit ...
    Viewing 1 result