Viewing 1 - 10 of 40 results
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- Chapter Name:
- Chapter 1: Basic Concepts in Immunology
- Description:
- In the initial stages of an immune response, the innate immune system recognizes the presence of pathogens and provides the first line of defense. Dendritic cells, which are circulating through the tissues, have the ability to ...
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- Chapter Name:
- Chapter 2: Innate Immunity: The First Lines of Defense
- Description:
- Activation of the complement system occurs on surfaces, such as the surface of a bacterium, as shown here. In this example, the activation of complement is initiated by antibodies that bind to bacterial cell surface antigens. The ...
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- Chapter Name:
- Chapter 3: The Induced Responses of Innate Immunity
- Description:
- The uptake of bacteria by phagocytes is an active process, which requires the triggering of specific receptors on the phagocyte. Fc receptors, which bind antibody-coated bacteria, are one of the receptors capable of triggering ...
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- Chapter Name:
- Chapter 3: The Induced Responses of Innate Immunity
- Description:
- Chemokine receptors are members of a very large family of receptors, all having seven transmembrane spanning regions. Each of these large family of receptors signals in the same way, by activating large GTP binding proteins, ...
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- Chapter Name:
- Chapter 3: The Induced Responses of Innate Immunity
- Description:
- Cells of the immune system, such as macrophages and dendritic cells, are the first line of defense in recognizing pathogens of various kinds. These cells have developed several kinds of receptors for recognizing different kinds of ...
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- Chapter Name:
- Chapter 3: The Induced Responses of Innate Immunity
- Description:
- In a healthy cell, the NOD like receptor called NALP3, also known as NLRP3, resides in the cytoplasm as a monomer. NALP3 has a pyrin domain at its amino terminus, and a domain of leucine rich repeats, also know as the LRR domain. ...
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- Chapter Name:
- Chapter 3: The Induced Responses of Innate Immunity
- Description:
- Neutrophils are white blood cells that hunt and kill bacteria. In this spread a neutrophil is seen in the midst of red blood cells. Staphylococcus aureus bacteria have been added. The small clump of bacteria release a ...
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- Chapter Name:
- Chapter 3: The Induced Responses of Innate Immunity
- Description:
- To visualize lymphocyte homing to a site of injury, a zebrafish larva was anesthetized and its fin pierced with a needle to introduce a small wound. A vein is seen at the bottom of the frame. Because the fin is very thin and ...
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- Chapter Name:
- Chapter 3: The Induced Responses of Innate Immunity
- Description:
- Leukocytes are white blood cells that help fight infection. At sites of injury, infection, or inflammation, cytokines are released and stimulate endothelial cells that line adjacent blood vessels. The endothelial cells then ...
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- Chapter Name:
- Chapter 3: The Induced Responses of Innate Immunity
- Description:
- Blood vessel endothelium at sites of infection expresses selectin molecules, P-selectin and E-selectin. Leukocytes, such as neutrophils, express the ligand for selectins, in the form of the sialylated Lewis X carbohydrate, S-Lex. ...
Viewing 1 - 10 of 40 results
