Viewing 1 - 10 of 27 results
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- Chapter Name:
- Chapter 1: Protein Structure and Evolution
- Description:
- Protein structures can be displayed in many different ways. A small protein domain, called the SH2 domain, is used here to demonstrate the different ways in which a protein structure can be displayed. The backbone view shows the ...
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- Chapter Name:
- Chapter 1: Protein Structure and Evolution
- Description:
- The beta sheet is another common secondary structure. In contrast to an alpha helix, it is formed by hydrogen bonds between backbone atoms on adjacent regions of the peptide backbone, called beta strands. These interactions do not ...
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- Chapter Name:
- Chapter 1: Protein Structure and Evolution
- Description:
- The alpha helix is one of the most common secondary structures in proteins. Amino acid side chains project outwards from the polypeptide backbone that forms the core of the helix. The chain is stabilized in this conformation by ...
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- Chapter Name:
- Description:
- Because of the geometry of its side chain, proline cannot readily fit into the regular structure of an α helix. Prolines are therefore often found in loops at the ends of α helices, acting as "helix breakers." Of the twenty ...
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- Chapter Name:
- Chapter 1: Protein Structure and Evolution
- Description:
- In a typical coiled-coil two alpha helices wrap around each other to form a stable structure. One side of each helix contains mostly aliphatic amino acids, such as leucines and valines, while the other side contains mostly polar ...
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- Chapter Name:
- Description:
- The bacterial potassium channel is a multipass transmembrane protein in the plasma membrane. It is built from four identical subunits that are arranged symmetrically. A pore in the center of the protein allows selective passage of ...
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- Chapter Name:
- Chapter 1: Protein Structure and Evolution
- Description:
- Hemagglutinin is a membrane fusion protein expressed on the surface of influenza viruses. By mediating the fusion of viral and cellular membranes during infection, it allows the viral genome to enter the cell. During the fusion ...
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- Chapter Name:
- Chapter 2: Protein Domains
- Description:
- Lysozyme is a small enzyme that binds to polysaccharide chains and breaks them apart by hydrolysis. It has two structural domains. One domain is composed mostly of alpha helices, while the other domain is composed mostly of beta ...
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- Chapter Name:
- Chapter 2: Protein Domains
- Description:
- Zinc finger domains are structural motifs used by a large class of DNA binding proteins. They use centrally coordinated zinc atoms as crucial structural elements. The zinc atom is coordinated by two cystine residues from the beta ...
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- Chapter Name:
- Chapter 3: Oligomers
- Description:
- Many proteins are composed of multiple polypeptide chains, or subunits. The Cro repressor, for example, is a homodimer formed of two identical subunits. The subunits join in a head-to-head fashion as two small beta sheets--one ...
Viewing 1 - 10 of 27 results
