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Genome Duplication

Genome Duplication - Melvin DePamphilis, Stephen Bell Enlarge
Edition:
1st
Author(s):
Melvin DePamphilis, Stephen Bell
ISBN:
9780415442060
Format:
Paperback
Publication Date:
October 06, 2010
Content Details:
450 pages | 243 illustrations
Language:
English

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List Price:   $147.00

  
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  • About the Book

    Book Summary

    Genome Duplication provides a comprehensive and readable overview of the underlying principles that govern genome duplication in all forms of life, from the simplest cell to the most complex multicellular organism.

    Using examples from the three domains of life - bacteria, archaea, and eukarya - Genome Duplication shows how all living organisms store their genome as DNA and how they all use the same evolutionary-conserved mechanism to duplicate it: semi-conservative DNA replication by the replication fork. The text shows how the replication fork determines where organisms begin genome duplication, how they produce a complete copy of their genome each time a cell divides, and how they link genome duplication to cell division.

    Genome Duplication explains how mistakes in genome duplication are associated with genetic disorders and cancer, and how understanding genome duplication, its regulation, and how the mechanisms differ between different forms of life, is critical to the understanding and treatment of human disease.

  • Contents

    1. Genomes 
    2. Three Domains of Life 
    3. Replication Forks 
    4. Replication Proteins: leading-strand synthesis 
    5. Replication Proteins: lagging-strand synthesis 
    6. Termination 
    7. Chromatin Assembly, Cohesion, and Modification 
    8. Replicons 
    9. Replication Origins 
    10. Origin Paradigms 
    11. Initiation 
    12. Cell Cycles 
    13. Checkpoints 
    14. Human Disease 
    15. Evolution of Cellular Replication Machines

  • Instructor Resources

    Instructor Resources

    For the following resources verified instructors can visit the resource page for Genome Duplication.

    The Art of Genome Duplication
    Artwork available in JPEG format.

  • E-book and Custom Pub

    E-book and Custom Publishing

    Genome Duplication is now available in the US and Canada as a downloadable e-book from VitalSource.

    VitalBook technology enables students to:
    • Search the text
    • Add highlights and notes, and share them
    • Download to multiple devices, including iPads

    The various e-book options for Genome Duplication enable students to save significantly over the printed version.
    • eBook purchase: $103.00 (30% off list price)
    • 1 year e-rental: $88.00 (40% off list price)
    • 180 day e-rental: $74.00 (50% off list price)

    To purchase or rent the e-book at the VitalSource store go to: http://store.vitalsource.com/show/978-1-1367-3823-4

     

    Garland Science Custom Publishing
    Garland Science Custom Publishing gives educators the ability to create their own course materials for use in the classroom-in e-book and/or print format. Faculty have complete control over what is added and may add chapters from Garland Science textbooks, web articles and blog postings, and self-authors content in PDF or Word format. Our site provides real-time copyright clearance, the ability to see a running total price as you build your book, and a cost savings for students.

    For more information visit http://www.garland.sharedbook.com.

  • Downloads

    Samples & Downloads

    Click on any of the links below to download a printable PDF of a sample chapter.

    Chapter 7: Chromatin Assembly, Cohesion, and Modification