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The Immune System

Peter Parham
Publication Date:
January 15, 2009
Content Details:
608 pages | 513 illustrations

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  • About the Book

    Book Summary

    The Immune System, Third Edition emphasizes the human immune system and synthesizes immunological concepts into a comprehensible, up-to-date, and reader-friendly account of how the immune system works. 

    Written for undergraduate, medical, veterinary, dental, and pharmacy students in immunology courses, it makes generous use of medical examples to illustrate points. 

    The Third Edition has been extensively revised and updated and includes two new chapters on innate and adaptive immunity, which explore the physical, cellular, and molecular principles underlying these responses to infection.  It also features enhanced coverage of aspects of innate immunity such as the complement system, Toll-like receptors, defensins, and C-reactive protein; the role of dendritic cells in initiating the primary adaptive immune response and the functions of other cells that bridge innate and adaptive immunity; immunotherapies using humanized monoclonal antibodies to treat certain diseases; and the nature of the immune response in the mucosal tissues and immunological memory.  The book offers over 500 full-color illustrations that complement and clarify the concepts.  The end-of-chapter questions have been expanded and include essay, multiple-choice, and case study questions, with answers provided at the end of the book.



      The Art of The Immune System, Third Edition: 978-0-8153-4429-2.

      • Question Bank: features over 500 essay and multiple choice questions and includes detailed answers to all questions.
      • Lecture outlines from the book's concept heads are available in PowerPoint®  format.


      • Completely updated throughout.
      • Chapter 2: Innate Immunity. Presents expanded coverage of innate immunity before discussion of adaptive immunity. Aspects of innate immunity such as Toll-like receptors, defensins, and C-reactive protein are explored.
      • Chapter 3: Principles of Adaptive Immunity. Covers the cellular and genetic principles underlying adaptive immunity.
      • Separate chapters now devoted to vaccination (Chapter 14), transplantation (Chapter 15), and cancer (Chapter 16).
      • The crucial role of dendritic cells in initiating the primary adaptive immune response is emphasized throughout.
      • The use of immunotherapies developed from humanized monoclonal antibodies as preferred treatments for certain diseases are discussed in several chapters.
      • The end-of-chapter questions have been significantly revised and now include essay, multiple choice, and case study questions.
      • Question Bank for instructors to accompany The Immune System, Third Edition. Includes over 500 questions organized by book chapter and designed for quiz and examination purposes.


      • Presents immunology from the human perspective with a central focus on how the immune system works to combat human disease.
      • Each chapter makes frequent use of medical examples to illustrate points and principles.
      • Seamless integration of the molecular, cellular, genetic and clinical facets of immunology.
      • An outstanding full-color art program including line drawings, micrographs and photographs. The art program, using distinct and consistent iconography, is designed to enhance and extend the concepts and principles presented in the text without overwhelming the reader with excessive detail.
      • End-of-chapter questions throughout the book. Questions consist of a mix of basic and clinical science. Detailed answers to all questions are provided in the back of the book.
      • End-of-section and end-of-chapter summaries provide a broad overview of material presented allowing students to review and assess their understanding of what they have read.



      "...Appealing and relevant for those students who approach the study of the immune system through a clinical lens, including students of medicine, pharmacology, midwifery, or nursing; it would also be appropriate in an introductory immunology course." -- Clinical Immunology, 113(3):345-6
  • Contents

    1. Elements of the Immune System and Their Roles in Defense
    2. Innate Immunity
    3. Principles of Adaptive Immunity
    4. Antibody Structure and the Generation of B-Cell Diversity
    5. Antigen Recognition by T Lymphocytes
    6. The Development of B Lymphocytes
    7. The Development of T Lymphocytes
    8. T Cell-Mediated Immunity
    9. Immunity Mediated by B Cells and Antibodies
    10. The Body’s Defenses Against Infection
    11. Failures of the Body’s Defenses
    12. Over-reactions of the Immune System
    13. Disruption of Healthy Tissue by the Immune Response
    14. Vaccination to Prevent Infectious Disease
    15. Transplantation of Tissues and Organs
    16. Cancer and its Interaction with the Immune System

  • Instructor Resources

    Instructor Resources

    For the following resources, verified instructors can visit the resource page for The Immune System, 3E.

    Art of The Immune System
    Artwork is available in PowerPoint and JPEG formats.

    Question Bank
    The Question Bank features over 500 essay and multiple choice questions and includes detailed answers to all questions. Prepared by Sheryl L. Fuller-Espie, Cabrini College, USA, the questions are organized by book chapter and designed for instructors to use for quiz and examination purposes. They measure knowledge of essential concepts and help student's link basic science to medical and research applications.

    Lecture Outlines
    Lecture outlines from the book’s concept headings are available in PowerPoint® format.

  • E-book and Custom Pub

    E-book and Custom Publishing


    The VitalBook e-book is available for purchase in its entirety or by chapter, or to rent for 1 year or 180 days, in the US and Canada from VitalSource.
    Purchase or rent in North America

    The Inkling media-integrated e-book contains figures optimized for digital display, assessments, and glossary definitions available with the tap of a finger or the click of a mouse.
    Purchase in North America

    Purchase in the Rest of World

    Garland Science Custom Publishing gives educators the ability to create their own course materials for use in the classroom-in e-book and/or print format. Faculty have complete control over what is added and may add chapters from Garland Science textbooks, web articles and blog postings, and self-authors content in PDF or Word format. Our site provides real-time copyright clearance, the ability to see a running total price as you build your book, and a cost savings for students.

    For more information visit

  • Downloads

    Samples & Downloads

    Download the Detailed Table of Contents from the book.

    Click on any of the links below to download a printable PDF of a sample chapter.

    Chapter 1: Elements of the Immune System and their Roles in Defense

    Download the correlation guide for Case Studies In Immunology, 6E and The Immune System, 3E.