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The Immune System

Peter Parham
Publication Date:
January 15, 2009
Content Details:
608 pages | 513 illustrations

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  • About the Book

    Book Summary

    The Immune System, Third Edition emphasizes the human immune system and synthesizes immunological concepts into a comprehensible, up-to-date, and reader-friendly account of how the immune system works. 

    Written for undergraduate, medical, veterinary, dental, and pharmacy students in immunology courses, it makes generous use of medical examples to illustrate points. 

    The Third Edition has been extensively revised and updated and includes two new chapters on innate and adaptive immunity, which explore the physical, cellular, and molecular principles underlying these responses to infection.  It also features enhanced coverage of aspects of innate immunity such as the complement system, Toll-like receptors, defensins, and C-reactive protein; the role of dendritic cells in initiating the primary adaptive immune response and the functions of other cells that bridge innate and adaptive immunity; immunotherapies using humanized monoclonal antibodies to treat certain diseases; and the nature of the immune response in the mucosal tissues and immunological memory.  The book offers over 500 full-color illustrations that complement and clarify the concepts.  The end-of-chapter questions have been expanded and include essay, multiple-choice, and case study questions, with answers provided at the end of the book.



      The Art of The Immune System, Third Edition: 978-0-8153-4429-2.

      • Question Bank: features over 500 essay and multiple choice questions and includes detailed answers to all questions.
      • Lecture outlines from the book's concept heads are available in PowerPoint®  format.


      • Completely updated throughout.
      • Chapter 2: Innate Immunity. Presents expanded coverage of innate immunity before discussion of adaptive immunity. Aspects of innate immunity such as Toll-like receptors, defensins, and C-reactive protein are explored.
      • Chapter 3: Principles of Adaptive Immunity. Covers the cellular and genetic principles underlying adaptive immunity.
      • Separate chapters now devoted to vaccination (Chapter 14), transplantation (Chapter 15), and cancer (Chapter 16).
      • The crucial role of dendritic cells in initiating the primary adaptive immune response is emphasized throughout.
      • The use of immunotherapies developed from humanized monoclonal antibodies as preferred treatments for certain diseases are discussed in several chapters.
      • The end-of-chapter questions have been significantly revised and now include essay, multiple choice, and case study questions.
      • Question Bank for instructors to accompany The Immune System, Third Edition. Includes over 500 questions organized by book chapter and designed for quiz and examination purposes.


      • Presents immunology from the human perspective with a central focus on how the immune system works to combat human disease.
      • Each chapter makes frequent use of medical examples to illustrate points and principles.
      • Seamless integration of the molecular, cellular, genetic and clinical facets of immunology.
      • An outstanding full-color art program including line drawings, micrographs and photographs. The art program, using distinct and consistent iconography, is designed to enhance and extend the concepts and principles presented in the text without overwhelming the reader with excessive detail.
      • End-of-chapter questions throughout the book. Questions consist of a mix of basic and clinical science. Detailed answers to all questions are provided in the back of the book.
      • End-of-section and end-of-chapter summaries provide a broad overview of material presented allowing students to review and assess their understanding of what they have read.



      "...Appealing and relevant for those students who approach the study of the immune system through a clinical lens, including students of medicine, pharmacology, midwifery, or nursing; it would also be appropriate in an introductory immunology course." -- Clinical Immunology, 113(3):345-6
  • Contents

    1. Elements of the Immune System and Their Roles in Defense
    2. Innate Immunity
    3. Principles of Adaptive Immunity
    4. Antibody Structure and the Generation of B-Cell Diversity
    5. Antigen Recognition by T Lymphocytes
    6. The Development of B Lymphocytes
    7. The Development of T Lymphocytes
    8. T Cell-Mediated Immunity
    9. Immunity Mediated by B Cells and Antibodies
    10. The Body’s Defenses Against Infection
    11. Failures of the Body’s Defenses
    12. Over-reactions of the Immune System
    13. Disruption of Healthy Tissue by the Immune Response
    14. Vaccination to Prevent Infectious Disease
    15. Transplantation of Tissues and Organs
    16. Cancer and its Interaction with the Immune System