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Protein Actions

Principles and Modeling

Edition:
1st
Author(s):
Ivet Bahar, Robert L. Jernigan, Ken A. Dill
ISBN:
9780815341772
Format:
Paperback
Publication Date:
February 09, 2017
Content Details:
322 pages | 107 illustrations
Language:
English

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List Price:   $109.00

  
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  • About the Book

    Book Summary

    Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers.

    The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.

    Features

      • 251 bold illustrations designed to help introduce and convey fundamental principles to readers from either biology or physics backgrounds
      • Emphasizes concepts and theory of proteins rather than experimental techniques
      • Gives the full breath of protein principles, bioinformatics, molecular simulations, and mechanisms
      • Some chapters contain appendices that elaborate on advanced material
  • Contents

    1. Proteins are Polymers that Fold into Specific Structures
    2. Proteins Perform Cellular Functions
    3. Proteins Have Stable Equilibrium Conformations
    4. Protein Binding Leads to Biological Actions
    5. Folding and Aggregation Are Cooperative Transitions
    6. The Principles of Protein Folding Kinetics
    7. Proteins Evolve
    8. Bioinformatics: Insights from Protein Sequences
    9. Protein Geometries and Energetics
    10. Molecular Simulations and Conformational Sampling
    11. Predicting Protein Structures from Sequences
    12. Biological Actions Arise from Protein Motions
    13. Molecular Modeling for Drug Discovery
  • Instructor Resources

    Instructor Resources

    Book figures available as JPEGs and powerpoint slides

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