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Janeway's Immunobiology

Edition:
8th
Author(s):
Kenneth Murphy
ISBN:
9780815342434
Format:
Paperback
Publication Date:
July 25, 2011
Content Details:
888 pages | 599 illustrations
Language:
English

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List Price:   $140.00

  
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  • About the Book

    Book Summary

    Janeway’s Immunobiology is a textbook that introduces the immune system in all its aspects to undergraduates, and also provides a treatment of the subject that is comprehensive enough to be useful to graduate students interested in research, and to medical students focused on clinical applications. The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.

    Janeway’s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout—that of the host’s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.

    Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.

    New in the Eighth Edition

    • Innate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook.  Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes).
    • The section on complement has been reworked and reconceived—explaining the lectin pathway first—making it easier to teach by placing it into the context of innate recognition.
    • Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms.
    • The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book.
    • Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen.
    • Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria.
    • Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways.
    • Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines.
    • Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text.
    • The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways.
    • New references have been added throughout the text.
  • Contents

    Part I: An Introduction to Immunobiology and Innate Immunity
    Chapter 1: Basic Concepts in Immunology
    Chapter 2: Innate Immunity: The First Lines of Defense
    Chapter 3: The Induced Responses of Innate Immunity

    Part II: The Recognition of Antigen
    Chapter 4: Antigen Recognition by B-cell and T-cell Receptors
    Chapter 5: The Generation of Lymphocyte Antigen Receptors
    Chapter 6: Antigen Presentation to T Lymphocytes

    Part III: The Development of Mature Lymphocyte Receptor Repertoires
    Chapter 7: Signaling Through Immune System Receptors
    Chapter 8: The Development and Survival of Lymphocytes

    Part IV: The Adaptive Immune Response
    Chapter 9: T Cell-Mediated Immunity
    Chapter 10: The Humoral Immune Response
    Chapter 11: Dynamics of Adaptive Immunity
    Chapter 12: The Mucosal Immune System

    Part V: The Immune System in Health and Disease
    Chapter 13: Failures of Host Defense Mechanisms
    Chapter 14: Allergy and Allergic Diseases
    Chapter 15: Autoimmunity and Transplantation
    Chapter 16: Manipulation of the Immune Response

  • Instructor Resources

    Instructor Resources

    For the following resources, verified instructors can visit the resource page for Janeway's Immunobiology, 8E.

    Animations and Videos
    For instructors we offer over 40 original immunological animations based on figures in the book and videos selected from visually compelling experiments. The animations have been revised and updated for this edition, and there are five new animations covering NALP3 Inflammasome, Isotype Switching, CD28, Crohn's Disease, and NFAT Activation and Cyclosporin. All the animations and videos are accompanied by a voice-over narration.

    The Art of Immunobiology
    The figures and tables from the book are available preloaded into PowerPoint presentations and as JPEGs.

    Lecture Outlines
    Lecture outlines are available in PowerPoint format.

  • Student Resources

    Student Resources

    For the following resources, students can visit the resource page for Janeway's Immunobiology, 8E.

    Animations and Videos
    For students we offer over 40 original immunological animations based on figures in the book and videos selected from visually compelling experiments. The animations have been revised and updated for this edition, and there are five new animations covering NALP3 Inflammasome, Isotype Switching, CD28, Crohn's Disease, and NFAT Activation and Cyclosporin. All the animations and videos are accompanied by a voice-over narration.

    Online Searchable Glossary

    Interactive Flashcards

     

  • E-book and Custom Pub

    E-book and Custom Publishing

    AMAZON KINDLE PRINT REPLICA E-BOOK

    VITALBOOK E-BOOK
    The VitalBook e-book is available for purchase in its entirety or by chapter, or to rent for 1 year or 180 days, in the US and Canada from VitalSource.
    Purchase or rent in North America

    INKLING E-BOOK
    The Inkling media-integrated e-book for Janeway's Immunobiology, Eighth Edition with Case Studies in Immunology, Sixth Edition contains figures optimized for digital display, animations and videos, quizzes and assessments, and glossary definitions available with the tap of a finger or the click of a mouse.
    Purchase in North America
    Purchase in the Rest of World

    GARLAND SCIENCE CUSTOM PUBLISHING
    Garland Science Custom Publishing gives educators the ability to create their own course materials for use in the classroom-in e-book and/or print format. Faculty have complete control over what is added and may add chapters from Garland Science textbooks, web articles and blog postings, and self-authors content in PDF or Word format. Our site provides real-time copyright clearance, the ability to see a running total price as you build your book, and a cost savings for students.

    For more information visit http://www.garland.sharedbook.com

  • Downloads

    Samples & Downloads

    Click on any of the links below to download a printable PDF of a sample chapter.

    Chapter 2: Innate Immunity: The First Lines of Defense