- Kenneth Murphy
- Publication Date:
- July 25, 2011
- Content Details:
- 888 pages | 599 illustrations
Also of Interest
Janeway’s Immunobiology is a textbook that introduces the immune system in all its aspects to undergraduates, and also provides a treatment of the subject that is comprehensive enough to be useful to graduate students interested in research, and to medical students focused on clinical applications. The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.
Janeway’s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout—that of the host’s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.
Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.
New in the Eighth Edition
- Innate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes).
- The section on complement has been reworked and reconceived—explaining the lectin pathway first—making it easier to teach by placing it into the context of innate recognition.
- Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms.
- The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book.
- Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen.
- Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria.
- Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways.
- Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines.
- Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text.
- The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways.
- New references have been added throughout the text.
Part I: An Introduction to Immunobiology and Innate Immunity
Chapter 1: Basic Concepts in Immunology
Chapter 2: Innate Immunity: The First Lines of Defense
Chapter 3: The Induced Responses of Innate Immunity
Part II: The Recognition of Antigen
Chapter 4: Antigen Recognition by B-cell and T-cell Receptors
Chapter 5: The Generation of Lymphocyte Antigen Receptors
Chapter 6: Antigen Presentation to T Lymphocytes
Part III: The Development of Mature Lymphocyte Receptor Repertoires
Chapter 7: Signaling Through Immune System Receptors
Chapter 8: The Development and Survival of Lymphocytes
Part IV: The Adaptive Immune Response
Chapter 9: T Cell-Mediated Immunity
Chapter 10: The Humoral Immune Response
Chapter 11: Dynamics of Adaptive Immunity
Chapter 12: The Mucosal Immune System
Part V: The Immune System in Health and Disease
Chapter 13: Failures of Host Defense Mechanisms
Chapter 14: Allergy and Allergic Diseases
Chapter 15: Autoimmunity and Transplantation
Chapter 16: Manipulation of the Immune Response
For the following resources, verified instructors can visit the resource page for Janeway's Immunobiology, 8E.
Animations and Videos
For instructors we offer over 40 original immunological animations based on figures in the book and videos selected from visually compelling experiments. The animations have been revised and updated for this edition, and there are five new animations covering NALP3 Inflammasome, Isotype Switching, CD28, Crohn's Disease, and NFAT Activation and Cyclosporin. All the animations and videos are accompanied by a voice-over narration.
The Art of Immunobiology
The figures and tables from the book are available preloaded into PowerPoint presentations and as JPEGs.
Lecture outlines are available in PowerPoint format.
For the following resources, students can visit the resource page for Janeway's Immunobiology, 8E.
Animations and Videos
For students we offer over 40 original immunological animations based on figures in the book and videos selected from visually compelling experiments. The animations have been revised and updated for this edition, and there are five new animations covering NALP3 Inflammasome, Isotype Switching, CD28, Crohn's Disease, and NFAT Activation and Cyclosporin. All the animations and videos are accompanied by a voice-over narration.
Online Searchable Glossary
E-book and Custom Publishing
AMAZON KINDLE PRINT REPLICA E-BOOK
The VitalBook e-book is available for purchase in its entirety or by chapter, or to rent for 1 year or 180 days, in the US and Canada from VitalSource.
Purchase or rent in North America
The Inkling media-integrated e-book for Janeway's Immunobiology, Eighth Edition with Case Studies in Immunology, Sixth Edition contains figures optimized for digital display, animations and videos, quizzes and assessments, and glossary definitions available with the tap of a finger or the click of a mouse.
Purchase in North America
Purchase in the Rest of World
NOOK STUDY E-BOOK – COMING SOON
GARLAND SCIENCE CUSTOM PUBLISHING
Garland Science Custom Publishing gives educators the ability to create their own course materials for use in the classroom-in e-book and/or print format. Faculty have complete control over what is added and may add chapters from Garland Science textbooks, web articles and blog postings, and self-authors content in PDF or Word format. Our site provides real-time copyright clearance, the ability to see a running total price as you build your book, and a cost savings for students.
For more information visit http://www.garland.sharedbook.com
Samples & Downloads
Click on any of the links below to download a printable PDF of a sample chapter.