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Physical Biology of the Cell

Edition:
2nd
Author(s):
Rob Phillips, Jane Kondev, Julie Theriot, Hernan Garcia
ISBN:
9780815344506
Format:
Paperback
Publication Date:
October 29, 2012
Content Details:
1,057 pages | 742 illustrations
Language:
English

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List Price:   $152.00

  
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  • About the Book

    Book Summary

    Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that unite a given set of biological phenomena. Herein lies the central premise: that the appropriate application of a few fundamental physical models can serve as the foundation of whole bodies of quantitative biological intuition, useful across a wide range of biological problems. The Second Edition features full-color illustrations throughout, two new chapters, a significantly expanded set of end-of-chapter problems, and is available in a variety of e-book formats.

    Features

      • New chapter on “Light and Life.” Describes the intersection of quantum mechanics and biology.
      • New chapter on “Biological Patterns: Order in Space and Time.” Studies pattern formation, critical to fields such as developmental biology and tissue engineering.
      • New boxes called “Computational Explorations.” These boxes complement the emphasis on analytic calculations with computational approaches.
      • Full-color illustrations throughout.
      • Significantly expanded end-of-chapter problems.
      • Further reading and references updated for each chapter.

    Reviews

      “The book is well illustrated, problems and references complete each chapter, figures and other data can be downloaded from the Garland Science Web site. Its public is assumed to be students taking a first course in physical biology or biophysics, and scientists interested in physical modelling in biology. Physical Biology of the Cell has much to offer to both categories…”
      - Crystallography Reviews

      “This textbook is an excellent resource, both for a research scientist and for a teacher. The authors do a superb job of selecting the material for each chapter and explaining the material with equations and narrative in an easily digestible manner.”—Yale Journal of Biology and Medicine (YJBM)

      Praise for the First Edition of Physical Biology of the Cell:

      Physical Biology of the Cell…aims to be both an introduction to molecular and cellular biology for physicists and an introduction to physics for biologists. Though that sounds like a daunting task, the book fully and impressively delivers. Physical Biology of the Cell might well become a similar classic [as Molecular Biology of the Cell] for anyone who heeds its mantra “quantitative data demand quantitative models.” It will give both physicists and biologists a useful introduction into the other camp’s methods and ways of thinking.”
      —Ralf Bundschuh, Physics Today, 2009

      “[The] authors of Physical Biology of the Cell have produced one of the first multi-purpose textbooks that is readily accessible to both physicists and biologists….When read from cover to cover, the book is both very instructive and highly entertaining, with the authors using humor to deliver strong take-home messages in each chapter....Physical Biology of the Cell provides instructors with excellent material to create a graduate level course in biology or physics.”
      —Patricia Bassereau and Pierre Nasoy, Nature Cell Biology, 2009

      Physical Biology of the Cell is beautifully crafted: self-contained and modular, it provides tutorials on fundamentals and has material to hold the interest of a more sophisticated reader. It is fast-paced, proceeding within each chapter from freshman basics to graduate level sophistication. To truly master the physics presented in the
      book, one should do the problems provided with each chapter. These problems are well thought out and are a major teaching resource.”
      —Boris Shraiman, Cell, 2009

      “…a monumental undertaking by three outstanding experts in the field…the book is a rich collection of special topics in biophysics…”
      —Gabor Forgacs, Quarterly Review of Biology, 2009

      “I would thoroughly recommend [Physical Biology of the Cell] to anyone interested in investigating or applying biophysical research methods to their work. It is likely to be a fantastic teaching tool and is a welcome addition in this age of increasingly
      interdisciplinary science.”
      —David Stephens, The British Society for Cell Biology Newsletter, 2009

  • Contents

    Part I: The Facts of Life

    1. Why: Biology by the Numbers
    2. What and Where
    3. When: Stopwatches at Many Scales
    4. Who: "Bless the Little Beasties"

    Part II: Life at Rest

    5. Mechanical and Chemical Equilibrium
    6. Entropy Rules!
    7. Two-State Systems
    8. Random Walks and the Structure of Macromolecules
    9. Electrostatics for Salty Solutions
    10. Beam Theory
    11. Biological Membranes

    Part III: Life in Motion

    12. The Mathematics of Water
    13. A Statistical View of Biological Dynamics
    14. Crowded and Disordered Environments
    15. Rate Equations and Dynamics in the Cell
    16. Dynamics of Molecular Motors
    17. Biological Electricity
    18. Light and Life – NEW CHAPTER

    Part IV: The Meaning of Life

    19. Organization of Biological Networks
    20. Biological Patterns: Order in Space and Time – NEW CHAPTER
    21. Sequences, Specificity, and Evolution
    22. Whither Physical Biology?

  • Instructor Resources

    Instructor Resources

    With the exception of the Solutions Manual, these resources are available on the Physical Biology of the Cell media website: http://microsite.garlandscience.com/pboc2/

    Figures and PowerPoint® Presentations
    The figures from the book are available in two convenient formats: PowerPoint and JPEG.

    Data Sets
    The original data used to create both the figures and homework problems are available in Excel® spreadsheets. With this data, the reader can extend the theoretical tools developed in the book to fit experimental data for a wide range of problems.

    Hints for Problems
    This PDF provides both hints and strategies for attacking some of the more difficult end-of-chapter problems.

    Matlab® and Mathematica® Code
    These files contain code for the “Computational Explorations” sidebars located throughout the book.

    Movies
    The movies complement the figures and discussion from the book by illustrating the rich dynamics exhibited by living organisms and the molecules that make them tick.

    Solutions Manual
    This PDF contains solutions to all problems in the book, available only to qualified instructors on the Garland Science Instructor Resource site.

  • Student Resources

    Student Resources

    The student resources are available at the Physical Biology of the Cell media website: http://microsite.garlandscience.com/pboc2/

    Figures and PowerPoint® Presentations
    The figures from the book are available in two convenient formats: PowerPoint and JPEG.

    Data Sets
    The original data used to create both the figures and homework problems are available in Excel® spreadsheets. With this data, the reader can extend the theoretical tools developed in the book to fit experimental data for a wide range of problems.

    Hints for Problems
    This PDF provides both hints and strategies for attacking some of the more difficult end-of-chapter problems.

    Matlab® and Mathematica® Code
    These files contain code for the “Computational Explorations” sidebars located throughout the book.

    Movies
    The movies complement the figures and discussion from the book by illustrating the rich dynamics exhibited by living organisms and the molecules that make them tick.

  • E-book and Custom Pub

    E-book and Custom Publishing

    Physical Biology of the Cell will also be available on Amazon Kindle Print Replica. More details will come soon.

    VITALBOOK E-BOOK
    The VitalBook e-book is available for purchase in its entirety or by chapter, or to rent for 1 year or 180 days, in the US and Canada from VitalSource.
    Purchase or rent in North America.

    Garland Science Custom Publishing
    Garland Science Custom Publishing gives educators the ability to create their own course materials for use in the classroom-in e-book and/or print format. Faculty have complete control over what is added and may add chapters from Garland Science textbooks, web articles and blog postings, and self-authors content in PDF or Word format. Our site provides real-time copyright clearance, the ability to see a running total price as you build your book, and a cost savings for students.

    For more information visit http://www.garland.sharedbook.com

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