Janeway’s Immunobiology, Seventh Edition is an introductory text for use in immunology courses for
undergraduates, graduate students, and medical students. It guides the reader through the immune system in all its aspects—from the first engagement of innate immunity to the generation of the adaptive immune response and its clinical consequences.
The Seventh Edition has been comprehensively updated throughout, and includes new information on topics such as NK cells, Toll-like receptors, AID, viral evasins, mucosal immunity, and celiac disease, to name a few. Each copy of the book includes a revised CD-ROM, Immunobiology Interactive, which contains animations and videos with voiceover narration, as well as the figures from the text in PowerPoint® and JPEG formats for presentation purposes. New discussion questions have been provided at the end of Chapters 2-16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. As in previous editions, a caduceus icon in margins indicates topics which are correlated to Case Studies in Immunology, Fifth Edition by Geha and Rosen.
Janeway’s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, full-color art program, scientific accuracy, and consistent viewpoint—that of the host’s interaction with an environment containing many species of potentially harmful microorganisms.
CONTAINS NEW INFORMATION ON:
- NK Cells
- New families of pattern recognition receptors for intracellular pathogens
- Updated treatment of Toll-like receptors and the increasing understanding of their role in immunology is brought out throughout the book
- AID and its role in class switching, gene conversion, somatic hypermutation
- Expanded treatment of cross presentation of antigens by dendritic cells
- Viral evasins and how they interrupt antigen processing pathways
- Updating of dendritic cell function and the dynamics of T-cell subsets during an immune response
- Detailed account of T-cell receptor activation and signaling pathways
- Updating of role of transcription factors in early B-cell development
- Streamlining lymphocyte development and separating the presentation of B-cell and T-cell development
- Expanded discussions of memory
- Separate chapter on mucosal immunity
- New research findings included on: AIDS, celiac disease, Crohn’s disease, immunological approaches to cancer treatment
- New findings on adaptive immune responses in lower organisms
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