Hallmark Features:

• Presents immunology from the human perspective with a central focus on how the immune system works to combat human disease.
• Each chapter makes frequent use of medical examples to illustrate points and principles.
• Seamless integration of the molecular, cellular, genetic and clinical facets of immunology.
• An outstanding full color art program including line drawings, micrographs and photographs. The art program, using distinct and consistent iconography, is designed to enhance and extend the concepts and principles presented in the text without overwhelming the reader with excessive detail.
• End-of-chapter questions throughout the book. Questions consist of a mix of basic and clinical science. Detailed answers to all questions are provided in the back of the book.
• End-of-section and end-of-chapter summaries provide a broad overview of material presented allowing students to review and assess their understanding of what they have read.

New in the Third Edition

• Completely updated throughout.
• Chapter 2: Innate Immunity. Presents expanded coverage of innate immunity before discussion of adaptive immunity. Aspects of innate immunity such as Toll-like receptors, defensins, and C-reactive protein are explored.
• Chapter 3: Principles of Adaptive Immunity. Covers the cellular and genetic principles underlying adaptive immunity.
• Separate chapters now devoted to vaccination (Chapter 14), transplantation (Chapter 15), and cancer (Chapter 16).
• The crucial role of dendritic cells in initiating the primary adaptive immune response is emphasized throughout.
• The use of immunotherapies developed from humanized monoclonal antibodies as preferred treatments for certain diseases are discussed in several chapters.
• The end-of-chapter questions have been significantly revised and now include essay, multiple choice, and case study (USMLE-format) questions.
• Question Bank for instructors to accompany The Immune System, Third Edition. Includes over 500 questions organized by book chapter and designed for quiz and examination purposes.